| 11:35 PM | Nightline: In-depth reporting on news and events with Cynthia McFadden, Terry Moran and Martin Bashir. |
| 12:06 AM | Jimmy Kimmel Live: Actor Martin Short; Solange Knowles performs. |
| 1:06 AM | Oprah Winfrey: Kent Whitaker tells how he learned his son was the mastermind behind the murder of his family. |
| 2:05 AM | Cribs: Singer Aaron Carter; model Kylie Bax; snowboarder Shaun White. |
| 2:35 AM | Local Programming |
| 3:05 AM | ABC World News Now: Global news. |
| 4:30 AM | America This Morning: Breaking news. |
| 5:00 AM | Local Programming |
| 7:00 AM | Good Morning America: Sarah Evans performs; political commentator James Carville; saving energy. |
| 9:00 AM | Live With Regis and Kelly: Gary Sinise; Sarah McLachlan performs; best toys of 2008. |
| 10:00 AM | Rachael Ray: New Kids on the Block; a hypnotist helps couples tackle costly issues; dinner fries. |
| 11:00 AM | The View: Actress Gretchen Mol; actress Tristan Rogers. |
| 12:00 PM | Local Programming |
| 12:30 PM | Who Wants to Be a Millionaire |
| 1:00 PM | All My Children: Aidan closely monitors Greenlee; Adam makes a move against Fusion; Taylor rebuffs Jake. |
| 2:00 PM | One Life to Live: Dorian wants Jackie McNaughton to get rid of Ray for good. |
| 3:00 PM | General Hospital: Ric warns Anthony about Johnny being out of control. |
| 4:00 PM | Oprah Winfrey: Dr. Oz answers questions about hair transplants, male menopause and sex. |
| 5:00 PM | Local Programming |
| 6:30 PM | ABC's World News With Charles Gibson: The latest world and national news. |
| 7:00 PM | Jeopardy! |
| 7:30 PM | Wheel of Fortune - Ultimate Adventures |
| 8:00 PM | Dancing With the Stars: One celebrity is eliminated. |
| 9:00 PM | Presidential Debate: In Nashville, candidates discuss issues. |
| 10:30 PM | ABC News Vote '08: Presidential Debate Analysis: Journalists and commentators analyze the presidential debate. |
| 11:00 PM | Local Programming |
| 11:35 PM | Nightline: In-depth reporting on news and events with Cynthia McFadden, Terry Moran and Martin Bashir. |