Episodes cast for
"Samantha Who?" (2007)

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Season: 1 | 2
Year: 2007 | 2008 | unknown

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Season 1

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Season 1, Episode 1: Pilot

15 October 2007
A woman suffering from amnesia tries to rediscover her life.

	Christina Applegate	...	Samantha
	Jennifer Esposito	...	Andrea Belladonna
	Kevin Dunn	...	Howard
	Melissa McCarthy	...	Dena
	Tim Russ	...	Frank
	Barry Watson	...	Todd
	Jean Smart	...	Regina Newly
	William Abadie	...	Rene
	Brett Rickaby	...	AA Leader
	Nakia Burrise	...	Dr. Kerry Hall (as Nakia R. Burrise)
	Adam Jennings	...	Barista
	Jelynn Rodriguez	...	Angry Woman
	Jill Talley	...	AA Female Leader
	Dan Thiel	...	Dave

Season 1, Episode 2: The Job

22 October 2007
When her friend says that she's in rehab, Samantha tries to go along with it as well as trying to figure out what she actually does for a living. Along the way, she discovers that she has a doctor's appointment, but not what she figures it to be for.

	Christina Applegate	...	Samantha Newly
	Jennifer Esposito	...	Andrea
	Kevin Dunn	...	Howard
	Melissa McCarthy	...	Dena
	Tim Russ	...	Frank
	Barry Watson	...	Todd
	Jean Smart	...	Regina Newly
	Rick Hoffman	...	Chase Chapman
	Joy Osmanski	...	Tracy
	Frank Maharajh	...	Dr. Kegoshian
	Dana Sorman	...	Jerri
	Jamison Haase	...	Vic
	B.J. Clinkscales	...	Waiter
	Jose Acevedo	...	Bar Patron (uncredited)
	Meggan Anderson	...	Coffee Girl (uncredited)
	Sema Batuk	...	Club Patron (uncredited)
	Aliza Pearl	...	Real Estate Executive (uncredited)

Season 1, Episode 3: The Wedding

29 October 2007
Samantha finds herself a bridesmaid in a wedding planned before her memory loss, only to arrive and find that she's not welcome.

	Christina Applegate	...	Samantha
	Jennifer Esposito	...	Andrea
	Kevin Dunn	...	Howard
	Melissa McCarthy	...	Dena
	Tim Russ	...	Frank
	Barry Watson	...	Todd
	Jean Smart	...	Regina Newly
	Jessica St. Clair	...	Valerie
	Gerald Downey	...	Paul
	Curt Cornelius	...	Trey Wells
	Amanda Young	...	Paul's Wife
	Kara Taitz	...	Bridesmaid

Season 1, Episode 4: The Virgin

5 November 2007
Beacause of her continuing amnesia, Samantha cannot remember anything about her sex life. So, she decides to embark on a personal quest to find the right guy to experiment with.

	Christina Applegate	...	Samantha Newly
	Jennifer Esposito	...	Andrea
	Kevin Dunn	...	Howard
	Melissa McCarthy	...	Dena
	Tim Russ	...	Frank
	Barry Watson	...	Todd
	Jean Smart	...	Regina Newly
	Ryan Carlberg	...	Jason
	Rand Holdren	...	Ryan
	Sarah Spiegel	...	Young Woman
	Tamas Menyhart	...	Kissing Couple (uncredited)
	Valentyna Svyatchenko	...	Kissing Couple (uncredited)

Season 1, Episode 5: The Restraining Order

12 November 2007
Samantha finds out she's had a restraining order placed on her and finds out about the strained relationship she's had with her father, all as a result of hearing a song from her past, not realizing what it's all about.

	Christina Applegate	...	Samantha
	Jennifer Esposito	...	Andrea
	Kevin Dunn	...	Howard
	Melissa McCarthy	...	Dena
	Tim Russ	...	Frank
	Barry Watson	...	Todd
	Jean Smart	...	Regina Newly
	Todd Grinnell	...	Nathan
	Johanna E. Braddy	...	Teenage Samantha (as Johanna Braddy)
	Tony Jones	...	Police Sergeant (as Anthony R. Jones)
	Jagger Chase	...	Kid
	Emma Degerstedt	...	Teenage Samantha
	Jarrod W. Robbins	...	Bartender (uncredited)

Season 1, Episode 6: The Hypnotherapist

19 November 2007
In an effort to recover her memories, Samantha turns to a hypno-therapist, only to find out that she might be adopted.

	Christina Applegate	...	Samantha
	Jennifer Esposito	...	Andrea
	Kevin Dunn	...	Howard
	Melissa McCarthy	...	Dena
	Tim Russ	...	Frank
	Barry Watson	...	Todd
	Jean Smart	...	Regina Newly
	Kelsey Lee Smith	...	Young Samantha (as Kelsey Smith)
	Dean Cochran	...	Fireman (uncredited)
	Visa May	...	Party Girl (uncredited)

Season 1, Episode 7: The Hockey Date

26 November 2007
After finding out she likes hockey, Samantha decides to get re-involved in her lost interest in an effort to impress a blind date in which her parents set her up. Andrea decides to go to Rome with her new-found boyfriend.

	Christina Applegate	...	Samantha
	Jennifer Esposito	...	Andrea Belladonna
	Kevin Dunn	...	Howard
	Melissa McCarthy	...	Dena
	Tim Russ	...	Frank
	Barry Watson	...	Todd
	Jean Smart	...	Regina Newly
	Kiele Sanchez	...	Chloe
	Joy Osmanski	...	Tracy
	Eddie Cibrian	...	Kevin
	Marilyn Sue Perry	...	Cashier
	Katie Lee Harper	...	Elevator Woman #1 (uncredited)
	Isis Harris	...	Lady in the Bar (uncredited)
	David Pearl	...	Doctor (uncredited)

Season 1, Episode 8: The Car

3 December 2007
Things are not as they seem as Samantha remembers what happened in the past after she dumps her father's car into the lake.

	Christina Applegate	...	Samantha
	Jennifer Esposito	...	Andrea Belladonna
	Kevin Dunn	...	Howard
	Melissa McCarthy	...	Dena
	Tim Russ	...	Frank
	Barry Watson	...	Todd
	Jean Smart	...	Regina Newly
	Arshad Aslam	...	Barista

Season 1, Episode 9: The Break Up

10 December 2007
Samantha's first night of intimacy with Kevin has her falling head over heels over the guy, and some drastic changes at work have her friends concerned, as well.

	Christina Applegate	...	Samantha
	Jennifer Esposito	...	Andrea Belladonna
	Kevin Dunn	...	Howard
	Melissa McCarthy	...	Dena
	Tim Russ	...	Frank
	Barry Watson	...	Todd
	Jean Smart	...	Regina Newly
	Joy Osmanski	...	Tracy
	Eddie Cibrian	...	Kevin
	Reggie Jordan	...	Flower Delivery Guy
	Timon Kyle	...	Russ (as Timon Kyle Durrett)
	Arshad Aslam	...	Barista (uncredited)

Season 1, Episode 10: The Girlfriend

7 April 2008

	Christina Applegate	...	Samantha
	Jennifer Esposito	...	Andrea Belladonna
	Melissa McCarthy	...	Dena
	Tim Russ	...	Frank
	Barry Watson	...	Todd
	Jean Smart	...	Regina Newly
	Kiele Sanchez	...	Chloe
	Beth Littleford	...	Audrey Rhodes
	Tanya Sinovec	...	Girl

Season 1, Episode 11: The Boss

14 April 2008

	Christina Applegate	...	Samantha
	Jennifer Esposito	...	Andrea Belladonna
	Kevin Dunn	...	Howard
	Melissa McCarthy	...	Dena
	Tim Russ	...	Frank
	Barry Watson	...	Todd
	Jean Smart	...	Regina Newly
	Rick Hoffman	...	Chase Chapman
	Jaclyn Kerhulas	...	Sign Language Interpreter
	Ossie Mair	...	Driver
	Timothy Olyphant	...	Winston Funk

Season 1, Episode 12: The Butterflies

21 April 2008
Sam uses the budding relationship between her boss and her friend, Dena, to stop a construction project that would destroy the home of an endangered species, while trying to figure out why Todd keeps ignoring her.

	Christina Applegate	...	Samantha
	Jennifer Esposito	...	Andrea Belladonna
	Kevin Dunn	...	Howard
	Melissa McCarthy	...	Dena
	Tim Russ	...	Frank
	Barry Watson	...	Todd
	Jean Smart	...	Regina Newly
	Rick Hoffman	...	Chase Chapman
	Joy Osmanski	...	Tracy
	Morgan Murphy	...	Woman Protester

Season 1, Episode 13: The Gallery Show

28 April 2008
Sam ponders over the idea of using the invitation she got from Todd send her for his gallery exhibit and wonders what kind of message she'll be giving by attending with someone else.

	Christina Applegate	...	Samantha
	Jennifer Esposito	...	Andrea
	Kevin Dunn	...	Howard
	Melissa McCarthy	...	Dena
	Tim Russ	...	Frank
	Barry Watson	...	Todd
	Jean Smart	...	Regina Newly
	Kiele Sanchez	...	Chloe
	Rick Hoffman	...	Chapman
	Ian Duncan	...	Cameron
	Brandon Ford Green	...	Guy
	Natasha Leggero	...	Woman Customer
	Jerry O'Connell	...	Craig
	Jim Rash	...	Artist
	Jonathan Schmock	...	Hipster

Season 1, Episode 14: The Affair

5 May 2008
All signs point to the fact that Samantha's mother is having an affair, while she sneaks around with Todd under Chloe's nose and Andrea ponders over the possibility of going into a partnership with Dena in acquiring a coffee shop.

	Christina Applegate	...	Samantha
	Jennifer Esposito	...	Andrea Belladonna
	Kevin Dunn	...	Howard
	Melissa McCarthy	...	Dena
	Tim Russ	...	Frank
	Barry Watson	...	Todd
	Jean Smart	...	Regina Newly
	Soledad Campos	...	Woman
	Gerard Sanders	...	Rory
	Anthony Winters	...	Man (as Tony Winters)

Season 1, Episode 15: The Birthday

12 May 2008
Sam decides she's through sneaking around with Todd, while Andrea and Sam's mother fight for the opportunity to put Sam's birthday party together.

	Christina Applegate	...	Samantha
	Jennifer Esposito	...	Andrea Belladonna
	Kevin Dunn	...	Howard
	Melissa McCarthy	...	Dena
	Tim Russ	...	Frank
	Barry Watson	...	Todd
	Jean Smart	...	Regina Newly
	Kiele Sanchez	...	Chloe
	Melody Butiu	...	Nurse
	Brian Catalano	...	Orderly

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Season 2

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Season 2, Episode 1: Out of Africa

12 August 2008

Wendy Allyn

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Aid Worker

Season 2, Episode 2: Episode #2.2

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Rick Hoffman

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Chase Chapman

Season 2, Episode 3: Episode #2.3

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Season 2, Episode 4: Episode #2.4

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Season 2, Episode 5: Episode #2.5

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	Rachel Cannon	...	Carol
	Rick Hoffman	...	Chase Chapman

Season 2, Episode 6: Episode #2.6

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Season 2, Episode 7: Episode #2.7

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